Join Us!
-
We are seeking a mission-aligned Imaging Scientist to develop, optimize and scale light microscopy workflows for large-scale image acquisition. This role combines sample preparation, advanced microscopy, quantitative image analysis, and engineering-driven technology development with the goal of improving imaging quality and robustness.
-
The role forms a critical part of our sample production pipeline and will be responsible for expansion microscopy development and iteratively improving protocols. Your work will drive two overarching outcomes: improving gel performance and improving the quality, reproducibility and scalability of sample production. This combines hands-on experimental work with defining quantitative metrics to assess mechanical and optical gel properties, image quality and pipeline throughput.
-
We are seeking a creative and mission-driven Machine Learning Scientist to develop scalable automatic proofreading methods leveraging barcode and shape information. In this role, you will own core ML pipelines for automated proofreading of neuron and synaptic reconstructions in optical connectomics datasets, working closely with wet lab scientists, microscopists, and domain experts to ensure biological fidelity and scalability. Your work will directly support E11’s goal of making reliable connectomic data accessible to the broader neuroscience community.
-
E11 Bio is seeking a motivated, mission-aligned Associate computational scientist to develop, maintain and optimize the workflows and infrastructure that process our large-scale brain mapping data. You will be responsible for keeping petabytes of imaging data moving reliably from the microscope to finished, processed volumes. That means helping maintain our data pipelines as well as being hands-on with the physical computing and network infrastructure. In addition, you will interact daily with biologists and microscopists on frontier research to identify new areas where scientific computing may accelerate their progress. For this you will build solutions that solve real problems at the bench: from quality control and real-time data analysis to agentic lab automation. This position is on-site only, in Alameda, CA.
-
If you are passionate about using your skills to advance neuroscience, think you may be a great fit for E11 Bio, but don’t see a role which looks tailored to you – we encourage you to apply to our general applicant pool. We routinely review resumes/CVs submitted through this channel.