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  • E11 Bio is seeking an experienced Director of Operations to manage and mentor a small ops team and provide operational leadership across the organization’s systems.

    This is a full-time, exempt leadership role responsible for ensuring scientific activities are supported by operational execution, managing the operations team, and building scalable systems that support E11’s continued growth. You will partner closely with scientific leadership to guide planning, manage risk, and ensure that ambitious technical goals are matched by operational rigor.

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  • E11 Bio is seeking an expert in light-sheet microscopy and large-volume imaging of optically cleared tissue to scale our imaging systems. In addition we are interested in increasing the information extracted per voxel through approaches such as combinatorial molecular encoding, spectral multiplexing, and multi-round readout strategies.

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  • E11 Bio is seeking a mission-aligned experimental scientist who is equally comfortable at the bench, the microscope, and with quantitative data analysis. This role is responsible for sample preparation end-to-end for high-quality connectomics, combining hands-on experimental work with quantitative image-based QC to diagnose failure modes and iteratively improve protocols. You will collaborate closely with molecular biology, imaging, and computational teams to ensure we consistently prepare high quality specimens and brain tissue to support our ambitious scaling goals towards whole-brain connectomics.

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  • We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.

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  • If you are passionate about using your skills to advance neuroscience, think you may be a great fit for E11 Bio, but don’t see a role which looks tailored to you –  we encourage you to apply to our general applicant pool.  We routinely review resumes/CVs submitted through this channel.

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